| MB 103 | Introductory Topics in Microbiology | 1(1-0-0) S |
| Introduction to scope and objectives of university education. Emphasis on microbiology. Career opportunities, computers, university resources. |
| Course Offerings: fall | WolfWare Info |
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| MB (BEC) 180 | Introduction to Applied Bioprocessing | 3(1-4-0) SUM1,SUM2 |
| Preq: Applicants should have completed the high school courses in chemistry and biology. Departmental approval required for current NCSU students. |
| Curricular bridge between high school and college for high school and transitional students. Fundamental cell biology concepts pertaining to biomanufacturing. Students gain an understanding of the basic principles of microbiology, culture preparation, physiology, and genetics of microbial cell cultures. Team-based decisions, collaborations and consideration of multiple perspectives are emphasized. Practical experience in laboratory and culture techniques used in biomanufacturing. Transportation will be provided for field trips. This course is part of the Summer College in Biotechnology and Life Sciences (SCIBLS), as well as other pre-college, transitional and early-college programs. Suitable for students with less than 30 credit hours. |
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| MB 200 | Microbiology and World Affairs | 3(3-0-0) |
| An integrated and comprehensive study of the microbial world and its influence on global events and human affairs. |
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| MB (BEC) 320 | Fundamentals of Microbial Cell Culture | 2(1.5-00.50-0) F,S |
| Preq: BIO 181 or BIO 183 or ZO 160 |
| This is a half-semester course. This introductory module addresses fundamental cell biology concepts and enables students to gain an understanding of the basic principles of microbiology, culture preparation, physiology and genetics of microbial cell cultures. The lab portion of the course provides students with practical experience in basic laboratory and culture techniques. Students who have completed MB 352 may not take this course for credit. |
| Course Offerings: fall sprg | |
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| MB (BEC) 325 | Fundamentals of Microbial Cell Biotransformations | 2(1.5-00.50-0) F,S |
| Preq: BEC(MB) 320 or MB 352 |
| This is a half-semester course. Basic microbial cell culture theory and practice: cell physiology, mass balances, and metabolic control as seen in a dynamic bioreactor culture. The biological understanding, mathematical models, and engineering controls that enable a bioreactor process to be scalable, consistent, and robust. The lab portion of the course provides students with hands-on experience in culture techniques using bioreactors. Students who have completed BIT(CHE) 463 may not take this course for credit. |
| Course Offerings: fall sprg | |
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| MB 351 | General Microbiology | 3(3-0-0) F,S,Sum |
| Preq: One biology course: (BIO 125,BIO 181, 183, ZO 150, or ZO 160) and one organic chemistry course: (CH 221 or CH 220) |
| Rigorous introduction to basic principles of microbiology for students in biological and agricultural sciences and for all students planning to take further courses in microbiology. |
| Course Offerings: fall sum2 sprg | WolfWare Info |
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| MB 352 | General Microbiology Laboratory | 1(0-3-0) F,S,Sum |
| Coreq: MB 351 |
| Laboratory experience in general microbiology. Aseptic technique, isolation and identification of bacteria, staining and microscopy. Enumeration of bacteria and viruses. |
| Course Offerings: fall sum2 sprg | WolfWare Info |
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| MB (FS) 405 | Food Microbiology | 3(3-0-0) |
| Preq: MB 351 |
| Microorganisms of importance in foods and their metabolic activities. Source of microbial contamination during food production, processing and storage. Microbial spoilage; foods as vectors of human pathogens. Physical and chemical destruction of microorganisms in foods and the kinetics involved. Conversions of raw foods by microorganisms into food products. Microbiological standards for regulatory and trade purposes. |
| Course Offerings: fall | |
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| MB (FS) 406 | Food Microbiology Lab | 1(0-2-1) |
| Coreq: FS (MB) 405 |
| Laboratory experience to complement FS/MB 405. Skills in detecting and quantitating microorganisms and their toxins in foods. Application of colony and direct microscopic counts, most probable numbers, enzyme immunoassays, nucleic acid probes and computer modeling are used to understand the numbers and types of microorganisms or microbial end products in foods. Laboratory safety and oral and written reports are emphasized. |
| Course Offerings: fall | |
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| MB 411 | Medical Microbiology | 3(3-0-0) F |
| Preq: MB 351 |
| Comprehensive study of microbial pathogenesis and mammalian host resistance. Diagnosis, prevention, and therapy of common human diseases of microbial origin. |
| Course Offerings: fall | WolfWare Info |
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| MB 412 | Medical Microbiology Laboratory | 1(0-3-0) F |
| Preq: MB 352 |
| Coreq: MB 411 |
| Laboratory experience to complement MB 411. Techniques of detection, growth and identification of bacteria and viruses relevant in clinical microbiology laboratories. Good laboratory practices (GLP) and safety stressed. |
| Course Offerings: fall | WolfWare Info |
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| MB 414 | Microbial Metabolic Regulation | 3(3-0-0) F |
| Preq: MB 351, BCH 451 |
| An integrative perspective on bacterial physiology and metabolism through an analysis of metabolic regulatory functions. |
| Course Offerings: fall | WolfWare Info |
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| MB 420 | Fundamentals of Microbial Cell Biotransformations | 2(1.5-00.50-0) F,S |
| Preq: BEC(MB) 320 or MB 352 |
| This is a half-semester course. Basic microbial cell culture theory and practice: cell physiology, mass balances, and metabolic control as seen in a dynamic bioreactor process to be scalable, consistent, and robust. The lab portion of the course provides students with hands-on experience in culture techniques using bioreactors. Students who have completed BIT (CHE) 463 may not take BEC (MB) 420 for credit. |
| Course Offerings: fall sprg | |
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| MB 441 | Immunology | 3(3-0-0) F |
| Preq: MB 351 |
| Introduction to principles of molecular immunology. Overview of immune system development and function, and discussions of ongoing scientific research regarding immune regulation. |
| Course Offerings: fall | |
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| MB 451 | Microbial Diversity | 4(3-3-0) S |
| Preq: SMB Majors, MB 411/412 and either GN 411 or BCH 451 |
| Molecular, biochemical and evolutionary diversity of the microbial world, including Bacteria (a.k.a. eubacteria), Archaea (archaebacteria), and unicellular Eucarya (eukaryotes). Evolutionary perspective on microbial relationships, molecular methodsof study and classical and modern biotechnological methods utilizing this genetic diversity to meet the needs of our own species. |
| Course Offerings: sprg | WolfWare Info |
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| MB 455 | Microbial Biotechnology | 3(3-0-0) S |
| Preq: MB 351, GN 411 |
| Introduction to industrial microbiology with focus on biotechnology including developments employing recombinant nucleic acid and monoclonal antibody techniques. Bioremediation, industrial enzymes, transgenic plants, biopesticides, medical diagnostics, recombinant vaccines production of important secondary metabolites, and other topics. Field trips to local biotechnology companies. |
| Course Offerings: sprg | WolfWare Info |
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| MB 461 | Introduction to Molecular Virology | 3(3-0-0) S |
| Preq: MB 351, MB 411 |
| Introduction to principles of molecular virology. Overview of classification and nomenclature, virus structure, interaction of viruses with cells, organisms (immunology, pathology), and populations (epidemiology). Detailed case studies from major groups of viruses; picornaviruses, togaviruses, orthomyxoviruses, retroviruses, polyomaviruses, and herpesviruses. |
| Course Offerings: sprg | WolfWare Info |
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| MB 490 | Seminar in Microbiology | 1(1-0-0) F,S |
| Preq: MB 351 and Senior standing |
| Library research on current topics in all areas of microbiology. Presentation of research results orally and in the form of a major term paper. |
| Course Offerings: fall sprg | |
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| MB 492 | External Learning Experience | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes facilities and resources which are external to the campus. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and the academic dean prior to the experience. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 493 | Special Problems in Microbiology | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes campus facilities and resources. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and the academic dean prior to the experience. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 495 | Special Topics in Microbiology | 1-3 F,S,Sum |
| Offered as needed to present materials not normally available in regular course offerings or for offering of new courses on a trial basis. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB (PB) (PP) 501 | Biology of Plant Pathogens | 3(3-0-0) F |
| Preq: PP 315, or PP 318, or an introductory course in microbiology |
| Biology of microbes that cause plant diseases. The ecology, genetics, physiology, taxonomy, and mechanisms of parasitism, pathogenicity and virulence of bacteria (and other prokaryotes), fungi (and oomycetes), nematodes, and viruses that cause plant diseases. Prepares graduate students for advanced courses in plant pathology, host-parasite interactions, and provides a knowledge base for students in other disciplines involved with plant pathogens or who seek to broaden their knowledge of microbes. |
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| MB (SSC) 532 | Soil Microbiology | 4(3-3-0) |
| Preq: MB 351, CH 220 |
| Soil as a medium for microbial growth, the relation of microbes to important mineral transformations in soil, the importance of biological equilibrium and significance of soil microbes to environmental quality. |
| Course Offerings: sprg | |
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| MB (PB) (PP) 575 | Introduction to Mycology | 4(3-3-0) F, Alt yrs(even) |
| Preq: BS 125 or BS 181 and 183 or BO 200 or PP 315 or PP 318 |
| A survey of the fungal kingdom in context of phyla and classes. Systematics, ecology, biology and utilization. Illustrative material, cultural techniques in laboratories. Collection and paper required. |
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| MB 590 | Topical Problems | 1-3 |
| Preq: Graduate standing, Consent of Instructor |
| Informal group discussion of prepared topics assigned by instructor. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 601 | Seminar | 1(1-0-0) F, S |
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| Course Offerings: fall sprg | WolfWare Info |
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| MB 610 | Special Topics Microbiology | 1-3 F,S,Sum |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 620 | Special Problems | 1-3 F, S, Sum |
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| Course Offerings: fall sum1 sum2 sprg | WolfWare Info |
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| MB 624 | Topical Problems | 1-3 F, S |
| Preq: Graduate standing, Consent of Instructor |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 670 | Laboratory Research Methods | 1-3 F, S |
| Preq: Consent of Instructor |
| Directed research of microbiology graduate students in departmental laboratories prior to selecting thesis research topic. Selection of a minimum of three laboratories for research experience lasting 3 to 5 weeks. Acquisition of research methods relevant to each laboratory. Microbiology graduate students only. |
| Course Offerings: fall sprg | |
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| MB 680 | Microbiology Research Presentations | 1(1-0-0) F, S |
| Essential elements of structure, delivery, data presentation and use of media in scientific research seminars. Presentation and evaluation of student seminars. Coverage of topical material in microbiology as determined by instructor. Microbiology graduate students only. |
| Course Offerings: fall | |
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| MB 685 | Master's Supervised Teaching | 1-3 F, S, Sum |
| Preq: Master's student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sum1 sum2 sprg | WolfWare Info |
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| MB 686 | Teaching Experience | 1(0-1-0) F, S, Sum |
| Preq: Microbiology Graduate student |
| Faculty mentoring in didactic and methodological aspects of teaching, including instructional technology as well as design and grading of assessment instruments. Provision of individual performance evaluations to encourage enhancement of teaching skills. Microbiology graduate students only. |
| Course Offerings: fall sum1 sum2 sprg | WolfWare Info |
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| MB 688 | Non-Thesis Masters Continuous Registration - Half Time Registration | 1(1-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc. |
| Course Offerings: sum1 sum2 sprg | |
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| MB 689 | Non-Thesis Master Continuous Registration - Full Time Registration | 3(3-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester. |
| Course Offerings: sum1 sum2 sprg | |
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| MB 690 | Master's Examination | 1-6 F, S, Sum |
| Preq: Master's student |
| For students in non thesis master's programs who have completed all other requirements of the degree except preparing for and taking the final master's exam. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 693 | Master's Supervised Research | 1-9 F, S, Sum |
| Preq: Master's student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 695 | Master's Thesis Research | 1-9 F, S, Sum |
| Preq: Master's student |
| Thesis research. |
| Course Offerings: fall sum1 sum2 sprg | WolfWare Info |
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| MB 696 | Summer Thesis Research | 1(1-0-0) Sum |
| Preq: Master's student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 | |
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| MB 699 | Master's Thesis Preparation | 1-3 F, S, Sum |
| Preq: Master's student |
| For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their theses. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 703 | Microbial Diversity | 2(2-0-0) S, Alt yrs |
| Preq: MB 351 |
| Introduction to theory and practice of bacterial taxonomy. Historical view of significant developments; classification into phrenetic and phylogenetic; modern approaches of chemotaxonomy and numerical taxonomy; identification methods; interactions and biotechnology, ecology, genetics and pathology. The role of microbial culture collections. |
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| MB 705 | Biological Scanning Electron Microscopy | 2(1-2-0) |
| Preq: Graduate standing with some biological background |
| On demand. Theory and application of scanning electron microscopy, including specimen preparation, microscope alignment and operation, performance evaluation, interpretation of problems and darkroom technique. (Limited to 8 students with prior approval of instructor.) |
| Course Offerings: sprg | |
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| MB 710 | Biological Transmission Electron Microscopy | 3(2-3-0) |
| Preq: Graduate standing with some biological background |
| On demand. Theoretical and practical aspects of transmission electron microscopy, including microscope alignment and use, performance evaluation, interpretation of problems and darkroom techniques. (Limited to 8 students with prior approval of instructor.) |
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| MB 711 | Ultramicrotomy For Life Sciences | 2(1-4-0) |
| Preq: MB 710, Graduate standing |
| On demand. An intensive laboratory course covering sample preparative techniques for transmission electron microscopy, including tissue preparation, thick sectioning, staining and ultramicrotomy. (Limited to 8 students with prior approval of instructor.) |
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| MB 714 | Microbial Metabolic Regulation | 3(3-0-0) F |
| Preq: MB 351, BCH 451 |
| An integrative perspective on bacterial physiology and metabolism through analysis of metabolic regulatory functions. Credit in both MB 414 and MB 714 is not allowed |
| Course Offerings: fall | WolfWare Info |
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| MB (PP) 715 | Applied Evolutionary Analysis of Population Genetic Data | 3(3-0-0) F, (ALTYRODD) |
| Preq: One or more of PP 707 & GN 703 & ST 501 |
| This course will introduce nonparametric and model-based methods for making inferences on population processes (mutation, migration, drift, recombination, and selection). The goal is to provide a conceptual overview of these methods and hands-on training on how to implement and interpret the results. Sample data sets in computer laboratories will integrate summary statistic, cladistic, coalescent, and bayesian approaches to examine population processes in different pathosystems with specificemphasis on eukaryotic microbes, viruses and bacteria. |
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| MB 718 | Introductory Virology | 3(3-0-0) F (alt yrs-odd) |
| Preq: BCH 451 or GN 411 or MB 351 |
| Introduction to principles of virology including: classification and nomenclature, epidemiology, structure, genome replication, gene expression strategies and cellular infection cycle. Major groups of viruses including those with DNA genomes and positive-sense or negative-sense RNA genomes. |
| Course Offerings: fall | WolfWare Info |
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| MB (FS) 725 | Fermentation Microbiology | 3(3-0-0) S Alt Yrs |
| Fermentation bioprocessing and characteristics, function and ecology of responsible microorganisms. Fermentative activities, growth responses and culture interactions related to metabolism, physiology and genetics of lactic acid bacteria and selected yeasts and molds. Current developments in starter culture technology and genetics; application to food and industrial fermentations. |
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| MB (GN) (PB) (PP) 730 | Fungal Genetics and Physiology | 3(2-3-0) S, Alt yrs |
| Preq: BCH 451, BO 775, GN 411 or PP 501 |
| Basic concepts of genetics and physiology of fungi, with emphasis on saprophytic and plant pathogenic mycelial fungi. Current literature on evolution, cell structure, growth and development, gene expression, metabolism, sexual and asexual reproduction and incompatibility systems. Laboratory exercises on mutant isolation, sexual and parasexual analysis, genetic transformation, and RFLP and isozyme analysis. |
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| MB 735 | Pathogenic Microbiology | 3(3-0-0) F |
| Preq: Graduate standing |
| Focuses on molecular mechanisms of bacterial pathogenesis: bacterial stategies to subvert host defenses; host defense mechanisms; virulence gene regulation; pathogen evolution. The course is lecture and research article based; it requires a written paper and an in-class presentation. |
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| MB (IMM) 751 | Immunology | 3(3-0-0) S |
| Preq: BCH 451, GN 411, MB 351 |
| Introduction to mechanisms of immunity in man and animals. Emphasis on interactions between cells of the immune system in production of immune responses and the molecules in control of these interactions. |
| Course Offerings: sprg | |
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| MB (CBS) (IMM) (PHY) (PO) 756 | Immunogenetics | 3(2-2-0) F, Alt yrs |
| Preq: MB 501C or MB 751 |
| Basic concepts of the immune system. Genetic basis of the immune response including immunoglobulin genetics, major histocompatibility complexes and their role in the immune response, the molecular basis of the immune system and effector mechanisms. |
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| MB (GN) 758 | Prokaryotic Molecular Genetics | 3(3-0-0) S |
| Preq: BCH 451, GN 411 |
| Structure and function in prokaryotic molecular genetics, with emphasis on mutations and mutagenic pathways, transcriptional and translational regulation, RNA processing, DNA replication and recombination and characterization of recombinant DNA molecules. Applications of genetic and recombinant DNA techniques to microbial processes, including strain construction and enhancement of gene expression. |
| Course Offerings: sprg | WolfWare Info |
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| MB 771 | Molecular Virology Of Animal Viruses | 3(3-0-0) F |
| Animal virus replication. Selected examples from each virus group illustrate principles underlying lytic, persistent and tumor-inducing viral infection. |
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| MB (PB) 774 | Phycology | 3(1-4-0) S |
| Introduction to taxonomy, morphology, reproduction and ecological importance of organisms which may be included in the algae. Attention to local freshwater flow and physiology of selected species in relation to algal blooms, water quality and nutrient loading in aquatic habitats. |
| Course Offerings: sprg | |
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| MB (CBS) (IMM) 783 | Advanced Immunology | 3(3-0-0) F, (ALTYRODD) |
| Preq: MB (IMM) 751 |
| In depth study of the basic cellular and molecular mechanisms of immunity, including antigen processing and presentation, T cell development, initiation of the immune response, effector mechanisms, and immunological memory. The course is designed for advanced graduate students who wish to focus on the current concepts in immunology. |
| Course Offerings: fall | |
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| MB 790 | Topical Problems | 3(3-0-0) F,S,Sum |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 801 | Seminar | 1(1-0-0) F, S |
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| Course Offerings: fall sprg | WolfWare Info |
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| MB 810 | Special Topics Microbiology | 1-3 F,S,Sum |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 820 | Special Problems | 1-3 F, S, Sum |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 824 | Topical Problems | 1-3 F, S |
| Preq: Graduate standing, Consent of Instructor |
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| Course Offerings: fall sum1 sum2 sprg | |
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| MB 870 | Doctoral Lab Rotations | 1-3 F, S |
| Directed research of microbiology graduate students in departmental laboratories prior to selecting thesis research topic. Selection of a minimum of three laboratories for research experience lasting 3 to 5 weeks. Acquisition of research methods relevant to each laboratory. Microbiology graduate students only. |
| Course Offerings: fall sprg | |
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| MB 880 | Doctoral Microbiology Research Presentations | 1(1-0-0) F, S |
| Preq: Consent of Instructor |
| Essential elements of structure, delivery, data presentation and use of media in scientific research seminars. Presentation and evaluation of student seminars. Coverage of topical material in microbiology as determined by instructor. Microbiology graduate students only. |
| Course Offerings: fall | WolfWare Info |
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| MB 885 | Doctoral Supervised Teaching | 1-3 F, S, Sum |
| Preq: Doctoral student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 886 | Teaching Experience | 1(0-1-0) F, S, Sum |
| Preq: Microbiology Graduate student |
| Faculty mentoring in didactic and methodological aspects of teaching, including instructional technology as well as design and grading of assessment instruments. Provision of individual performance evaluations to encourage enhancement of teaching skills. Microbiology graduate students only. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 890 | Doctoral Preliminary Examination | 1-9 F, S, Sum |
| Preq: Doctoral student |
| For students who are preparing for and taking written and/or oral preliminary exams. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 893 | Doctoral Supervised Research | 1-9 F, S, Sum |
| Preq: Doctoral student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 895 | Doctoral Dissertation Research | 1-9 F, S, Sum |
| Preq: Doctoral student |
| Dissertation research. |
| Course Offerings: fall sum1 sum2 sprg | |
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| MB 896 | Summer Dissertation Research | 1(1-0-0) Sum |
| Preq: Doctoral student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 | |
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| MB 899 | Doctoral Dissertation Preparation | 1-3 F, S, Sum |
| Preq: Doctoral student |
| For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations. |
| Course Offerings: fall sum1 sum2 sprg | |