| GN 301 | Genetics in Human Affairs | 3(3-0-0) F,S,Sum |
| Appreciation and understanding of genetics in everyday life. Genetic perspective on normal human development, birth defects, birth control, cancer, organ transplants, intelligence, mental illness, and radiation and chemical exposure and issues raised by applications of recently developed genetic techniques such as in vitro fertilization, genetic engineering and prenatal monitoring. |
| Course Offerings: fall sprg | |
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| GN 311 | Principles of Genetics | 4(3-0-1) F,S,Sum |
| Preq: BIO 183 or ZO 160 |
| Basic concepts and principles of prokaryotic and eukaryotic genetics. Mendelian inheritance, polygenic inheritance, linkage and mapping, chromosome aberrations, population genetics, evolution, DNA structure and replication, gene expression, mutation, gene regulation, extranuclear inheritance, bacterial and viral genetics, and recombinant DNA technology. Sophomore standing or permission of the instructor. |
| Course Offerings: fall | |
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| GN 412 | Elementary Genetics Laboratory | 1(0-3-0) F,S |
| Coreq: GN 411 |
| Genetic experiments and demonstrations using a variety of bacterial, plant and animal organisms. Mendelian inheritance, linkage analysis, population genetics, cytogenetics, biochemical genetics, DNA isolation, electrophoresis, and Southern blotting. |
| Course Offerings: fall sprg | WolfWare Info |
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| GN 413 | Advanced Genetics | 3(3-0-0) F,S |
| Preq: GN 411 |
| Biological macromolecules and their interactions. Chromatin and chromosome structure. Bacteria, viruses, plants, animals and fungi as genetic systems. Transcription, RNA processing, genetic code, translation, DNA replication and the cell cycle. RFLP mapping. DNA and forensics. Molecular genetics of disease. Genetic transformation and cloning of plants and animals. Recombinant DNA methodology. Students cannot receive credit for both GN 413 and GN 513 |
| Course Offerings: fall | WolfWare Info |
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| GN 414 | Genes and Development | 3(3-0-0) S |
| Preq: GN 411 |
| Genes and genetic pathways that control development in animals; overview of early, pivotal experiments in embryology and genetics; use of molecular biology, genomics and bioinformatics to study genes and development; concentration on four model systems; presentation and discussion of major issues in developmental biology. |
| Course Offerings: fall sprg | WolfWare Info |
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| GN 415 | Genome Science | 3(3-0-0) S |
| Preq: GN 411 |
| Complementation of modern genomics approaches with classical and molecular genetics; goals of major genome projects in animals, plants, humans, and microorganisms; genomic science opportunities at NCSU and in the Research Triangle; presentation and discussion of current literature; and preparation for careers in genomics-related fields. |
| Course Offerings: sprg | |
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| GN 492 | External Learning Experience | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes facilities and resources which are external to the campus. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and the academic dean prior to the experience. |
| Course Offerings: fall sum1 sum2 sprg | |
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| GN 493 | Special Problems in Genetics | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes campus facilities and resources. Arrangements must be initiated by student and approved by a faculty adviser and the departmental teaching coordinator. |
| Course Offerings: fall sum1 sum2 sprg | |
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| GN 495 | Special Topics in Genetics | 1-3 F,S,Sum |
| Offered as needed to present materials not normally available in regular course offerings or for offering of new courses on a trial basis. |
| Course Offerings: fall | |
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| GN 504 | Human Genetics | 3(3-0-0) F |
| Preq: GN 301 or 411 |
| Basic principles needed for an understanding of genetics of man. Current knowledge and important areas of research in human genetics. |
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| GN 513 | Advanced Genetics | 3(3-0-0) F,S |
| Preq: GN 411 |
| Biological macromolescules and their interactions. Chromatin and chromosome structure. Bacteria, viruses, plants, animals and fungi as genetic systems. Transcription, RNA processing, genetic code, translation, DNA replication and cell cycle. RFLP mapping. DNA and forensics. Genetic transformation and cloning of plants and animals. Recombinant DNA methodology. Credit for both GN 413 and GN 513 is not allowed. |
| Course Offerings: fall | |
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| GN (ENT) 527 | Insect Neurogenomics | 3(3-0-0) S (ALTYREVEN) |
| Preq: GN 413/513 |
| Sensory processing systems in the insect brain (visual, olfactory, gustatory, and mechanosensory), learning and memory and circadian rhythm. Each process will be considered at the behavioral, anatomical, neural, and genetic level. Examples will bedrawn from multiple insect species, using recent studies. Techniques: quantitative real-time PCR, microarrays, mapping quantitative trait loci, Drosophila transgenics, RNAi, imaging neuronal activity, etc. For Graduate students with background in molecular biology techniques. |
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| GN 685 | Master's Supervised Teaching | 1-3 F,S |
| Preq: Master's student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sprg | |
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| GN 688 | Non-Thesis Masters Continuous Registration - Half Time Registration | 1(1-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc. |
| Course Offerings: fall sprg | |
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| GN 689 | Non-Thesis Master Continuous Registration - Full Time Registration | 3(3-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester. |
| Course Offerings: fall sprg | |
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| GN 690 | Master's Examination | 1-6 F,S |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all other requirements of the degree except preparing for and taking the final master's exam. |
| Course Offerings: fall sprg | |
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| GN 693 | Master's Supervised Research | 1-9 F,S |
| Preq: Master's Student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sprg | |
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| GN 695 | Master's Thesis Research | 1-9 F,S |
| Preq: Master's Student |
| Thesis Research |
| Course Offerings: fall sprg | |
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| GN 696 | Summer Thesis Research | 1(1-0-0) Sum |
| Preq: Master's student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 | |
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| GN 699 | Master's Thesis Preparation | 1-3 F,S |
| Preq: Master's Student |
| For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis. |
| Course Offerings: fall sum1 sum2 sprg | |
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| GN 701 | Molecular Genetics | 3(3-0-0) F |
| Preq: GN 411 |
| A discussion of the structure and function of genetic material at a molecular level. Consideration of both prokaryotic and eukaryotic systems. The aim to describe genetics in terms of chemical principles. |
| Course Offerings: fall | WolfWare Info |
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| GN 702 | Cellular and Developmental Genetics | 3(3-0-0) S |
| Preq: GN 701 |
| Regulation of genes involved in cellular function, differentiation and development in eukaryotes. Presentation of biological systems and model organisms used to study genetic control of cellular and developmental processes. |
| Course Offerings: sprg | |
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| GN 703 | Population and Quantitative Genetics | 3(3-0-0) S |
| Preq: GN 411, ST 512 |
| Mutation and origin of genetic variation. Measuring genetic variation in natural populations. Gene and genotype frequencies. Hardy-Weinberg equilibrium. Values, means, genetic and environmental variance, heritability of quantitative traits. Random genetic drift and inbreeding. Natural and artifical selection. Theory and tests of models of maintenance of genetic variation. Molecular evolution of genes and proteins. Genome evolution. |
| Course Offerings: sprg | WolfWare Info |
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| GN (ANS) 708 | Genetics of Animal Improvement | 3(3-0-0) S |
| Preq: GN 411, ST 512 |
| Emphasis on the utilization of basic principles of population and quantitative genetics in animal improvement. Factors affecting genic and genotypic frequencies and methods of estimating genetic and nongenetic variance, heritabilities and breeding values. The roles of mating systems and selection procedures in producing superior genetic populations. |
| Course Offerings: fall | |
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| GN (ANS) 713 | Quantitative Genetics and Breeding | 3(3-0-0) F |
| Quantitative and population genetic theory of breeding problems; partitioning of genetic variance, maternal effects, genotype by environment interaction and genetic correlation; selection indexes; design and analysis of selection experiments; marker-assisted selection. |
| Course Offerings: fall | |
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| GN (CS) 719 | Origin and Evolution Of Cultivated Plants | 1(1-1-0) |
| Preq: CS(GN,HS)741; GN 511 |
| Review of concepts of speciation and classification; origin and variation in plants; theories related to agricultural origins; variation patterns of cultivated species; evolution under domestication; utilization of wild and unadapted germplasm in plant breeding. |
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| GN (CS) (HS) 720 | Molecular Biology In Plant Breeding | 3(0-3-0) S. (Alt. yrs.) |
| Preq: CS(GN,HS) 741, GN 701 |
| Theory and principles of molecular biology applied to plant breeding. Experimental approaches to induce genetic change, cytoplasmic recombination, haploid utilization and potentials of molecular techniques for solving breeding problems. |
| Course Offerings: sprg | |
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| GN (ST) 721 | Genetic Data Analysis | 3(3-0-0) S. (Alt. yrs.) |
| Preq: ST 430 and GN 411 |
| Analysis of discrete data, illustrated with genetic data on morphological characters allozymes, restriction fragment length polymorphisms and DNA sequences. Maximum likelihood estimation, including iterative procedures. Numerical resampling. Development of statistical techniques for characterizing genetic disequilibrium and diversity. Measures of population structure and genetic distance. Construction of phylogenetic trees. Finding alignments and similarities between DNA sequences. Locating genes with markers. |
| Course Offerings: sprg | |
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| GN (FOR) 725 | Forest Genetics | 3(3-0-0) S |
| Preq: GN 411 |
| Application of genetic principles to silviculture, management and wood utilization. Emphasis on variation in wild populations, the bases for selection of desirable qualities and fundamentals of controlled breeding. |
| Course Offerings: sprg | |
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| GN (FOR) 726 | Advanced Topics In Quantitative Genetics | 3(3-0-0) F. (Alt. yrs.) |
| Preq: GN(FOR) 725, GN(ST) 770 or GN(ANS) 713 |
| Advanced topics in statistics and population genetics pertinent to current research problems in genetics with special applications to forestry. Basic statistical and genetic theory reviewed as bases for intensive study of selection theory and experimental and mating design evaluation. Study of genetics of natural populations for evolutionary interest as well as for their implications to breeding theory. |
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| GN (MB) (PB) (PP) 730 | Fungal Genetics and Physiology | 3(2-3-0) S. (Alt. yrs.) |
| Preq: BCH 451, BO 775, GN 411 or PP 501 |
| Basic concepts of genetics and physiology of fungi, with emphasis on saprophytic and plant pathogenic mycelial fungi. Current literature on evolution, cell structure, growth and development, gene expression, metabolism, sexual and asexual reproduction and incompatibility systems. Laboratory exercises on mutant isolation, sexual and parasexual analysis, genetic transformation, and RFLP and isozyme analysis. |
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| GN 735 | Functional Genomics | 3(3-0-0) F |
| Preq: GN 411, Graduate standing |
| Methodology of experimental genomics; genome sequencing, gene expression arrays, genomic screens, proteomics. Aims and achievements of microbial, plant, animal, human genome projects. Applications of genomics including parasitology, breeding, functional genomics, evolutionary genetics. Interface with bioinformatics, data technology. |
| Course Offerings: sprg | WolfWare Info |
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| GN (ZO) 740 | Evolutionary Genetics | 3(3-0-0) F, Alt yr(even) |
| Preq: GN 703 |
| Genetic basis of evolution. Molecular evolution, molecular population genetics, evolutionary genetics of quantitative characters and the genetics of speciation. Critical reading of original research publications and student seminars. |
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| GN (CS) (HS) 745 | Quantitative Genetics In Plant Breeding | 1(1-0-0) S. (Alt. yrs.) |
| Preq: CS(GN, HS) 741, ST 512, course in quantitative genetics recommended |
| Theory and principles of plant quantitative genetics. Experimental approaches of relationships between type and source of genetic variability, concepts of inbreeding, estimations of genetic variance and selection theory. |
| Course Offerings: sprg | |
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| GN (CS) (HS) 746 | Breeding Methods | 2(2-0-0) S, Alt yrs |
| Preq: CS (GN, HS) 741, ST 512 |
| Theory and principles of plant breeding methodology including population improvement, selection procedures, genotypic evaluation, cultivar development and breeding strategies. |
| Course Offerings: sprg | |
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| GN (CS) (HS) (PP) 748 | Breeding For Pest Resistance | 2(2-0-0) F, Alt yrs |
| Preq: CS(GN, HS) 741, PP 315, ST 512 |
| Theory and principles of breeding for pest resistance. Experimental approaches for examining genetics of host-parasite interactions, expression and stability of pest resistance and breeding strategies for developing pest-resistant cultivars. |
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| GN 750 | Developmental Genetics | 3(3-0-0) S. (Alt. yrs.) |
| Preq: GN 701, GN 702 |
| Action and regulation of genes and gene-products in development and differentiation. Examples from microorganisms, plants and animals. Emphasis on molecular and biochemical aspects of mechanisms controlling gene expression in eukaryotic cell differentiation. |
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| GN 755 | Population Genetics | 3(3-0-0) S. (Alt. yrs.) |
| Preq: GN 703 |
| Theoretical population genetics and its relationship to natural and experimental populations. Single locus and multilocus systems, history of a gene in a population, diffusion approximations, suitability of models to natural and experimental populations. |
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| GN (ST) 756 | Computational Molecular Evolution | 3(3-0-0) F (Alt. yrs) |
| Preq: GN 411 and ST 511 |
| Phylogenetic analyses of nucleotide and protein sequence data. Sequence alignment, phylogeny reconstruction and relevant computer software. Prediction of protein secondary structure, database searching, bioinformatics and related topics. Project required. |
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| GN (ST) 757 | Statistics for Molecular Quantitative Genetics | 3(3-0-0) F, Alt Yr.(even) |
| Preq: ST 512 and GN 703 or ST 721 |
| Genetic mapping data. Linkage map reconstruction, quantitative genetical models. Statistical methods and computer programs for mapping quantitative trait loci and estimating genetic architecture of quantitative traits. |
| Course Offerings: fall | |
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| GN (MB) 758 | Prokaryotic Molecular Genetics | 3(3-0-0) S |
| Preq: BCH 451 or GN 411 |
| Structure and function in prokaryotic molecular genetics, with emphasis on mutations and mutagenic pathways, transcriptional and translational regulation, RNA processing, DNA replication and recombination and characterization of recombinant DNA molecules. Applications of genetic and recombinant DNA techniques to microbial processes, including strain construction and enhancement of gene expression. |
| Course Offerings: sprg | WolfWare Info |
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| GN (MB) 760 | Experimental Microbial Genetics | 4(2-6-0) S |
| Preq: GN 411, MB 351 |
| Laboratory-oriented presentation of current methodologies and concepts in molecular microbial genetics and their application to strain construction, plasmid and phage manipulations, mutagenesis, cloning and genetic engineering of microorganisms. |
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| GN (BCH) 761 | Advanced Molecular Biology Of the Cell | 3(3-0-0) S, Alt yrs |
| Preq: BCH 703 and 705 |
| An advanced treatment involving integrated approaches to biological problems at the molecular level, encompassing biochemistry, cell biology and molecular genetics. Broad, multidisciplinary approaches to solving research problems in biology and thecritical study of primary scientific literature, the development of a research proposal, oral presentations and class discussions. |
| Course Offerings: sprg | |
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| GN (BCH) 768 | Nucleic Acids: Structure and Function | 3(3-0-0) S, Alt yrs |
| Preq: BCH 701 and 703 |
| An advanced treatment involving integrated approaches to biological problems at the molecular level, encompassing biochemistry, cell biology and molecular genetics. Broad, multidisciplinary approaches to solving research problems in biology and thecritical study of primary scientific literature, the development of a research proposal, oral presentations and class discussions. |
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| GN (ST) 770 | Statistical Concepts In Genetics | 3(3-0-0) S, Alt yrs |
| Preq: GN 703 |
| Coreq: ST 512 |
| Migration, mutation, selection, drift, linkage, mating system and other processes bearing on rates of change in population frequencies, means and variances; magnitude and nature of genotypic and nongenotypic variability and their role in alternativeprocedures of plant and animal breeding; experimental and statistical approaches to the analysis of quantitative inheritance. |
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| GN 801 | Seminar | 1(1-0-0) F,S |
| Preq: Graduate standing |
| Informal group discussion of prepared topics assigned by instructor. |
| Course Offerings: fall sprg | |
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| GN 809 | Colloquium in Genetics | 2(2-0-0) F,S |
| Preq: Graduate standing |
| Informal group discussion of prepared topics assigned by instructor. |
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| GN 810 | Special Topics in Genetics | 1-4 F,S |
| Critical study of selected areas and special topics of current interest in genetics and related fields. |
| Course Offerings: fall sprg | |
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| GN 820 | Special Problems | 1-3 F,S |
| Preq: Advanced Graduate standing |
| Special topics designed for additional experience and research training. |
| Course Offerings: fall | |
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| GN 850 | Professionalism and Ethics | 1(1.5-0-0) F |
| Preq: Graduate standing |
| The course is designed to give students background in professionalism, scientific ethics and responsible conduct of science. Topics include the role of the scientist in society, ethical theory, data acquisition and ownership, scientific midconduct,authorship, peer review, conflicts of interest and commitment, intellectual property, ethics of teaching and mentoring, ethical treatment of animal and human subjects, ethics of genetics research, job hunting and interviewing. |
| Course Offerings: fall | WolfWare Info |
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| GN (CS) (HS) 860 | Plant Breeding Laboratory | 1(1-0-0) S, Alt yrs |
| Preq: CS(GN,HS)741 |
| Visitation of plant breeding projects in the Depts. of CS and HS at NC State, along with commercial seed companies. Discussion and viewing of breeding objectives, methods and equipment and teaching and practice of hybridization methods. |
| Course Offerings: sprg | |
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| GN (CS) (HS) 861 | Plant Breeding Laboratory | 1(1-0-0) F, Alt yrs |
| Preq: CS(GN,HS)741 |
| Visitation of plant breeding projects in the Depts. of CS and HS at NC State, along with commercial seed companies. Discussion and viewing of breeding objectives, methods and equipment and teaching and practice of hybridization methods. |
| Course Offerings: fall | |
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| GN 885 | Doctoral Supervised Teaching | 1-3 F,S |
| Preq: Doctoral student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sprg | |
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| GN 890 | Doctoral Preliminary Examination | 1-9 F,S |
| Preq: Doctoral student |
| For students who are preparing for and taking written and/or oral preliminary exams. |
| Course Offerings: fall sprg | |
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| GN 893 | Doctoral Supervised Research | 1-9 F,S |
| Preq: Doctoral student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sprg | |
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| GN 895 | Doctoral Dissertation Research | 1-9 F,S |
| Preq: Doctoral student |
| Dissertation Research |
| Course Offerings: fall sum1 sprg | |
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| GN 896 | Summer Dissertation Research | 1(1-0-0) Sum |
| Preq: Doctoral student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 | |
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| GN 899 | Doctoral Dissertation Preparation | 1-3 F,S |
| Preq: Doctoral student |
| For students who have completed all credit hour requirements, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations. |
| Course Offerings: fall sum1 sum2 sprg | |