CBS -Comparative Biological Sc


CBS 554Princ Analyt EpidemUNITS: 3


CBS 565Fundamentals of Biomedical SciencesUNITS: 3 - Offered in Fall Only
Introductory course for students interested in gaining a broad understanding of: comparative genomics, comparative immunology, comparative physiology, pharmacokinetics, emerging zoonotic diseases, epidemiology and translational research models and methods. This course also provides an overview of current technologies relevant to comparative biomedical research and a foundation for implementing the scientific method (e.g. experimental design, data analyses, statistics). Priority will be given tofirst-year students in CBS graduate program; Enrollment of all students requires consent of instructor.


CBS 570Methods in Biomedical SciencesUNITS: 1 - Offered in Fall Only
Introductory course for students interested in gaining a broad understanding of various laboratory methods used in molecular, cellular and "omics" based biomedical research.


CBS 580Clinical Veterinary EpidemiologyUNITS: 3 - Offered in Fall Only
Prerequisite: ST 511
To expose students to the concepts and principles of epidemiology from the perspective of assessing health and disease in animal and human populations, and the measures to control disease status. Specifically to study the principles and concepts ofveterinary epidemiology, to learn basic epidemiology methodology, critically review major veterinary care studies, and enhance oral and written communication skills.


CBS 595Special TopicsUNITS: 1-3


CBS (ANS) (PHY) (ZO) 602Seminar In Biology Of ReproductionUNITS: 2 - Offered in Spring Only
Prerequisite: ANS(PHY) 702
Current topics in animal reproduction presented by reproductive physiologists from various Research Triangle institutions. Student presentations of research projects or library projects in area of animal reproduction.


CBS 610Special Topics In Veterinary Medical SciencesUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Senior standing or Graduate standing
Designed to present new or special subject matter within the scope of pathology, veterinary microbiology, morphology or pharmacology. The studies may include independent investigations, seminars and/or formal lectures.


CBS 620Special ProblemsUNITS: 1-3 - Offered in Fall and Spring


CBS 662Professional Conduct in Biomedical ResearchUNITS: 1 - Offered in Spring Only
Plagiarism, authorship, fraud, safety, sexual harassment, IACUC, consulting agreements, serving as an expert witness, contacting elected officials, working with press, human subjects committee, and related topics.


CBS 685Master's Supervised TeachingUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Master's student
Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.


CBS 688Non-Thesis Masters Continuous Registration - Half Time RegistrationUNITS: 1 - Offered in Fall Spring Summer
Prerequisite: Master's student
For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc.


CBS 689Non-Thesis Master Continuous Registration - Full Time RegistrationUNITS: 3 - Offered in Fall Spring Summer
Prerequisite: Master's student
For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester.


CBS 693Master's Supervised ResearchUNITS: 1-9 - Offered in Fall Spring Summer
Prerequisite: Master's student
Instruction in research and research under the mentorship of a member of the Graduate Faculty.


CBS 695Master's Thesis ResearchUNITS: 1-9 - Offered in Fall Spring Summer
Prerequisite: Master's student
Thesis research


CBS 696Summer Thesis ResearchUNITS: 1 - Offered in Summer
Prerequisite: Master's student
For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.


CBS 699Master's Thesis PreparationUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Master's student
For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis.


CBS 730Veterinary HistologyUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Prerequisite: BCH 451
The structure of cells, tissues and organs of domestic animals using light microscopy.


CBS 731Applied Veterinary Anatomy IUNITS: 4 - Offered in Fall Only, Offered Alternate Years
Prerequisite: DVM
Graduate veterinarian provided with detailed anatomic information relevant to surgical and medical problems in domestic carnivores. Designed for graduate veterinarians in pursuit of advanced training in areas of anatomy, physiology, surgery, radiology and pathology.


CBS 732Biological Light and Electron Microscopy:Principles and PracticeUNITS: 5
Prerequisite: Graduate standing
Principles and applications of various tools for the optical visualization of cells and tissues, with information about how to best ascertain structure-function relationships. Introduction to sample preparation for light and electron microscopy, microtomy, and the theory and utilization of transmission-and scanning electron microscopes, light microscopes and confocal laser scanning microscopes. In addition, cytochemistry, cryotechniques, immunocytochemistry, digital imaging techniques, telemedicine, and silver-based photography techniques will be covered.


CBS 740Research Animal Care and UseUNITS: 3 - Offered in Spring Only, Offered Alternate Years
Principles of selection, care and use of animals in laboratory teaching and investigation presented. Topics including ethics of animal experimentation, selection of animal models, biology and care of laboratory animals, techniques of administration of substances and obtaining of specimens, producing surgical alterations and common laboratory animal health problems.


CBS 742Advanced Systemic HistopathologyUNITS: 2 - Offered in Spring Only, Offered Alternate Years
Prerequisite: Graduate standing and DVM Majors
Alt. yrs. Histopathologic changes associated with diseases of various organ systems. Emphasis on pathogenesis and morphologic changes associated with selected diseases.


CBS 743Toxicologic Pathology IUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Prerequisite: DVM Majors
A review of principles and practices of toxicologic pathology and a survey of common spontaneous and chemically induced lesions by organ systems with emphasis on recognition and interpretation.


CBS 751Pathogenic Bacteriology and MycologyUNITS: 3 - Offered in Fall Only
Prerequisite: MB 411, Graduate standing
Lecture covering pathogenic bacteria and fungi important in medicine. Lectures supplemented by laboratory exercises providing students the opportunity to learn basic characteristics of these microorganisms and how they are isolated, cultivated and identified.


CBS 752Diagnostic Bacteriology and MycologyUNITS: 3 - Offered in Fall and Spring
Prerequisite: Graduate standing
Presentation of principles of specimen collection, selection and use of media, culture processing and identification of bacteria and fungi important in animal disease.


CBS 753Veterinary ImmunologyUNITS: 2 - Offered in Spring Only
Prerequisite: MB 501C and Graduate standing
Basic and clinical immunology. Discussion of role of the immune system in disease prevention, inflammation and autoimmune diseases.


CBS 754Principles Of Analytical EpidemiologyUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Prerequisite: Graduate standing
Principles of epidemiology related to investigation of disease involving agent-host-environment concepts. Stress on epidemiological techniques and experimental design. Main focus on descriptive, analytical and experimental epidemiology pertinent to disease etiology and prevention.


CBS (IMM) 755ImmunoparasitologyUNITS: 2 - Offered in Spring Only, Offered Alternate Years
Prerequisite: MB 751
Helminth and protozoal parasite immune evasion and immunomodulation; consequences of parasite-induced immunopathogenesis; learning from failed attempts to develop protective vaccines against protozoa and helminths.


CBS (IMM) (MB) (PHY) (PO) 756ImmunogeneticsUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Prerequisite: MB 501C or MB 751
Basic concepts of the immune system. Genetic basis of the immune response including immunoglobulin genetics, major histocompatibility complexes and their role in the immune response, the molecular basis of the immune system and effector mechanisms.


CBS (VPH) 760Molecular Technologies for Epidemiologic InvestigationUNITS: 3 - Offered in Spring Only
Prerequisite: Introductory Epidemiology
The course is designed to help students refine their ability to select and interpret molecular diagnostic technologies for epidemiologic disease surveillance and investigation.


CBS 762Principles of PharmacologyUNITS: 3 - Offered in Spring Only
The action of drugs in animals and man including basic principles of drug disposition, pharmacokinetics, drug resistance, and signal transduction. Modification of physiological processes by drugs influencing nervous, renal, cardiovascular, and endocrine systems and the antimicrobic and antineoplastics agents.


CBS (ANS) (NTR) (PHY) 764Advances in Gastrointestinal PathophysiologyUNITS: 3 - Offered in Fall Only, Offered Alternate Odd Years
Prerequisite: PHY 503, PHY 504
This course will focus on advanced gastrointestinal physiology and the pathophysiology of deseases of relevance to scientsts involved in animal-related research. In particular, the course will cover the pathophysiology of ulceration, infectious diarrhea, ischemia, motility disorders, and inflammatory diseases of the gut. An in-depth review paper will be required based on recent literature rgarding a specific gastrointestinal disease.


CBS 770Cell BiologyUNITS: 3 - Offered in Spring Only
Prerequisite: BCH 451, BIO 183, CH 223
Advanced cell and organelle structure and function and recent advances in molecular biology. Emphasis on current literature and application of research procedures.


CBS (TOX) 771Cancer BiologyUNITS: 4 - Offered in Fall Only
Prerequisite: CBS 770
A comprehensive graduate course focusing on the molecular and cellular bases of cancer. Targets of oncogenic mutations will be discussed as well as their impact on cell proliferation, cell survival, and the invasion of normal tissues by tumorigeniccells. State-of-the-art technologies to detect oncogenic mutations and characterize transformed cells will be discussed as well as therapeutic strategies for the rational treatment of cancer.


CBS 773Advanced Developmental BiologyUNITS: 2 - Offered in Fall and Spring
In-depth coverage of current concepts and new research technologies in developmental biology. Biochemical aspects of germ cell maturation and early development, molecular and genetic regulation of morphogenesis, cellular interaction for organogenesis, hormones and growth factors mediated cellular differentiation and growth, molecular basis of neoplasia apopotises and gene therapy.


CBS 774Epidemiology Of Infectious Diseases Of International ImportanceUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Discussion of infectious diseases and epidemiological principles. Stress on selected enteric, zoonotic, nosocomial diseases of worldwide importance. Consideration of population dynamic techniques related to host-vector-agent.


CBS 780Veterinary Production EpidemiologyUNITS: 2 - Offered in Spring Only
Examination of tools, limits, advantages and disadvantages specific to veterinary epidemiology and its execution. Assessment of means of disease prevention and outbreak investigation; mathematical simulation and economics; plus monitoring and evaluation of disease control programs; use of a multiple-species orientation. Application of the above epidemiologic techniques and their roles in assisting producers, practitioners and regulators.


CBS 782Marine Mammal MedicineUNITS: 2 - Offered in Fall Only
Prerequisite: Graduate standing or enrollment in DVM curriculum
Discussion of disease issues in free ranging and captive cetaceans, pinnipeds and marine mustelids with emphasis on species found in North American waters. Examination of anatomic, physiologic and behavioral basis of health and population managementand assessment of diagnostic and therapeutic approaches to disease in these species.


CBS (IMM) (MB) 783Advanced ImmunologyUNITS: 3 - Offered in Fall Only, Offered Alternate Odd Years
Prerequisite: MB (IMM) 741
In depth study of the basic cellular and molecular mechanisms of immunity, including antigen processing and presentation, T cell development, initiation of the immune response, effector mechanisms, and immunological memory. The course is designed for advanced graduate students who wish to focus on the current concepts in immunology.


CBS 785Advanced and Molecular PharmacologyUNITS: 2
Prerequisite: CBS 762
A course for graduate students providing a comprehensive investigation of current topics in Pharmacology with an emphasis on molecular and cellular approaches in lecture and discussion formats. Faculty will introduce each subject area and students will read recent articles, present seminars, and write professional-grade papers.


CBS 787PharmacokineticsUNITS: 3 - Offered in Fall Only, Offered Alternate Years
Prerequisite: CBS 560, working knowledge of calculus
Mathematical models to describe disposition of drugs and toxic chemicals in the animal body. Areas including classic compartmental and nonlinear models as well as physiological approaches. Discussion of application of these techniques to toxicologicstudies.


CBS 790Special Topics in Clinical PathologyUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Those holding the DVM degree
New, fundamental and in-depth understanding of selected topics in clinical pathology (blood coagulation, acid-base balance, hematology, cytology, and clinical chemistry). A new topic selected each semester. Students read pertinent current journal articles and references and lead weekly discussion sessions. Stress upon clinical spplication of this information.


CBS 795Special Topics in Comparative Biomedical SciencesUNITS: 1-3
Prerequisite: Graduate Students, DVM or equivalent degree
Special Topics in Comparative Biomedical Sciences


CBS 800CBS SeminarUNITS: 1 - Offered in Fall Only
Presentation and discussions on ongoing research and current topics in biomedical sciences.


CBS (ANS) (PHY) (ZO) 802Seminar In Biology Of ReproductionUNITS: 2 - Offered in Spring Only
Prerequisite: ANS(PHY) 702
Current topics in animal reproduction presented by reproductive physiologists from various Research Triangle institutions. Student presentations of research projects or library projects in area of animal reproduction.


CBS 803Seminar in Surgical PathologyUNITS: 1 - Offered in Fall Spring Summer
Prerequisite: Those holding the DVM or equivalent degree
Description and interpretation of microscopic changes in tissues from diseased domestic and laboratory animals. Students attend and participate in a one-hour weekly seminar where microscopic lesions described, interpreted and discussed.


CBS 804Seminar in Necropsy PathologyUNITS: 1 - Offered in Fall Spring Summer
Prerequisite: Those holding the DVM or equivalent degree
Description and interpretation of gross changes in tissues from diseased domestic animals. Students attend daily (M-F) 15-to 30-minute review of necropsy lesions presented by a member of the graduate staff.


CBS 806Seminar in Cell BiologyUNITS: 1 - Offered in Fall and Spring
Prerequisite: Graduate standing
Presentation and discussions of ongoing research and current topics in cell biology.


CBS (IMM) 807Seminar in Veterinary Microbiology/ImmunologyUNITS: 1 - Offered in Fall and Spring
Presentation of ongoing research and current topics in microbiology.


CBS 810Special TopicsUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Senior standing or Graduate standing
Designed to present new or special subject matter within the scope of pathology, veterinary microbiology, morphology or pharmacology. The studies may include independent investigations, seminars and/or formal lectures.


CBS 812Special Topics PathologyUNITS: 1-4 - Offered in Fall and Spring
Prerequisite: Those holding the DVM degree
Specific topics of study assigned in various laboratories involved in veterinary microbiology investigation. Students conduct in-dept studies of assigned problem areas.


CBS 813Special Topics Laboratory PharmologyUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Graduate standing
Involvement in practical participation in the normal research activities of different laboratories working in pharmacological research. Students pursue a semi-independent project.


CBS 815Advanced Topics in VirologyUNITS: 1 - Offered in Fall Only, Offered Alternate Even Years
Prerequisite: VMM 924 or MB 718
Selected topics of current interest in virology. A new topic selected each time course is offered to keep the advanced gradute students up to date on the most recent developments in these fields.


CBS (IMM) 816Advanced Topics In ImmunologyUNITS: 1 - Offered in Fall Spring Summer
Prerequisite: MB 751
Selected topics of current interest in immunology. A different topic will be covered each semester to focus on the most recent developments in the field.


CBS 817Advanced Topics In Zoological Medicine IUNITS: 2 - Offered in Fall Only
Prerequisite: Graduate standing or enrollment in DVM curriculum
Selected topics of current interest in clinical zoological medicine focused on marine mammals, fish, reptiles, amphibians, waterfowl, ratites, raptors and medical issues in free-ranging wildlife. Review of current clinical and basic science literature, student-lead discussion sessions and participation in faculty-lead discussions.


CBS 818Advanced Topics in Zoological MedicineUNITS: 2 - Offered in Spring Only
Prerequisite: Graduate standing or enrollment in DVM curriculum
This course provides breadth and depth of knowledge in zoological medicine to prepare Zoological Medicine residents to pass American College of Zoological Medicine (ACZM) boards. Veterinary students are exposed to more in depth information related to zoological medicine than covered in their core curriculum. Each Fall (CBS 817) and Spring (CBS 818) semesters, different aspects of zoological medicine are covered. Topics rotate every 3 years so that all major groups of animals within the sub-groups, avian, aquatic, herptile, wildlife, and zoo are addressed.


CBS 820Special ProblemsUNITS: 1-3 - Offered in Fall and Spring


CBS 860Techniques in Pharmacological ResearchUNITS: 2 - Offered in Fall Only
Prerequisite: BCH 452B or CH 315 and Graduate standing
Theory and applications of modern scientific instrumentation to analysis of tissues, body fluids and drugs in pharmacological research. Discussion of appropriate aspects of the pharmacological use of spectroscopy, microscopy, chromatography, electrophoresis, radioisotope usage and centrifugation.


CBS 861Bacterial Pathogenic MechanismsUNITS: 2 - Offered in Spring Only, Offered Alternate Years
Discussion of principles of pathogenesis and host-response in bacterial infections of animals.


CBS 885Doctoral Supervised TeachingUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Doctoral student
Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.


CBS 886One Health: From Philosophy to PracticeUNITS: 2 - Offered in Fall and Spring
Graduate/professional seminar (with team project) addressing intersections of veterinary medicine, human medicine, and environmental health. Co-listed at UNC CH Gillings School of Global Public Health and Duke University School of Medicine. Includes participants from these three institutions, plus related private-sector members, non-governmental organizations, and government professionals. Its purpose is to facilitate understanding of one health as a system of systems, and promote cross-campus and cross-discipline interactions. Weekly evening course held at NC Biotechnology Center, RTP. Requires graduate student standing at NCSU or professional student standing within the College of Veterinary Medicine. Limit: 15 students per university.


CBS 890Doctoral Preliminary ExaminationUNITS: 1-9 - Offered in Fall Spring Summer
Prerequisite: Doctoral student
For students who are preparing for and taking written and/or oral preliminary exams.


CBS 893Doctoral Supervised ResearchUNITS: 1-9 - Offered in Fall Spring Summer
Prerequisite: Doctoral student
Instruction in research and research under the mentorship of a member of the Graduate Faculty.


CBS 895Doctoral Dissertation ResearchUNITS: 1-9 - Offered in Fall Spring Summer
Prerequisite: Doctoral student
Dissertation research.


CBS 896Summer Dissertation ResearchUNITS: 1 - Offered in Summer
Prerequisite: Doctoral student
For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.


CBS 899Doctoral Dissertation PreparationUNITS: 1-3 - Offered in Fall Spring Summer
Prerequisite: Doctoral student
For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.