| BCH (MB) 101 | Introduction to Microbiology and Biochemistry Laboratory Practices | 3(1-4-0) SUM1,SUM2 |
| Curricular bridge between high school and college for high school and transitional students. A "hands on" introduction to fundamentals in Microbiology and Biochemistry. Bacterial isolation, identification and growth using aseptic technique, microscopy, and metabolic analysis. Experiments with DNA isolation and analysis, protein isolation, and purification, and enzyme kinetics. Lectures and readings on background, theory and applications of these techniques. Field trips to university and industry research laboratories. This course is part of the Summer College in Biotechnology and Life Sciences (SCIBLS) as well as other pre-college, transitional and early-college programs and is offered as 4 week intensive course. Applicants should have completed high school courses in biology and chemistry. Students must have completed no more than 30 credit hours. Departmental approval is required for current NCSU students. |
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| BCH 220 | Role of Biotechnology in Society | 3(10-0-0) SUM1, SUM2 |
| Preq: BIO 181, CH 101 |
| Biotechnology and Societing is an introductory science course that takes a semi-technical look at the emerging role of biotechnology in human society. Expectations are that students will gain an appreciation for biotechnology, the ability to understand how biotechnology works. Offered only in Poland through Study Abroad (4-week course). Departmental approval required. |
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| BCH 451 | Principles of Biochemistry | 4(3-0-1) F,S,Sum |
| Preq: CH 223 |
| Introduction to the fundamental principles of biochemistry. Emphasis on biochemical structures, properties, functions and interactions, including enzyme kinetics and central pathways of metabolism. |
| Course Offerings: fall sum2 sprg | WolfWare Info |
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| BCH 452 | Introductory Biochemistry Laboratory | 2(1-3-0) F,S |
| Coreq: BCH 451 |
| Laboratory experience to complement BCH 451. Basic skills in the use of volumetric equipment, spectrophotometers, chromatography, and electrophoresis. Manipulation and assay of small quantities of biological materials, and analysis of laboratory data. |
| Course Offerings: fall sum1 sprg | |
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| BCH 453 | Biochemistry of Gene Expression | 3(3-0-0) F,S |
| Preq: BCH 451 |
| Coreq: GN 411, MB 351 |
| Structure and function of nucleic acids and proteins. Synthesis of DNA, RNA, and proteins. Gene expression and Regulation. Methodologies of recombinant DNA research. Credit is not allowed for both BCH 453 and BCH 553. |
| Course Offerings: fall sprg | WolfWare Info |
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| BCH 454 | Advanced Biochemistry Laboratory | 4(1-8-0) F |
| Preq: BCH 452 |
| Coreq: BCH 453 |
| Techniques in molecular biology and protein purification. Cloning and expression of a eukaryotic gene in bacteria followed by purification of the eukaryotic gene product. Microanalysis of DNA, RNA and protein. |
| Course Offerings: fall sprg | |
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| BCH 455 | Proteins and Molecular Mechanisms | 3(3-0-0) S |
| Preq: BCH 451, BCH 453/553 |
| Principles of protein structure and function, protein folding, enzymology, ligand binding, protein transport, and metabolic pathways. |
| Course Offerings: fall sprg | WolfWare Info |
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| BCH 492 | External Learning Experience | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes facilities and resources which are external to the campus. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and academic dean prior to the experience. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 493 | Special Problems in Biochemistry | 1-6 F,S |
| Preq: Sophomore standing |
| A learning experience in agriculture and life sciences within an academic framework that utilizes campus facilities and resources. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and the academic dean prior to the experience. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 495 | Special Topics in Biochemistry | 1-5 F,S,Sum |
| Preq: Junior standing |
| Offered as needed to present materials not normally available in regular BCH departmental courses or for new BCH courses on a trial basis. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 552 | Experimental Biochemistry | 3(1-6-0) F |
| Preq: BCH 452;BCH 453 |
| An advanced laboratory to give students practical experiences in purification and quantitative characterization of enzymes and nucleic acids. Studies with carbohydrates and membrane lipids. Credit may be applied toward biotechnology minor. |
| Course Offerings: fall sprg | |
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| BCH 553 | Biochemistry of Gene Expression | 3(3-0-0) F,S |
| Preq: BCH 451 |
| Coreq: GN 411, MB 351 |
| Structure and function of nucleic acids and proteins. Synthesis of DNA, RNA, and proteins. Gene expression and Regulation. Methodologies of recombinant DNA research. Credit in both BCH 453 and BCH 553 is not allowed. |
| Course Offerings: fall sprg | WolfWare Info |
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| BCH 555 | Proteins and Molecular Mechanisms | 3(3-0-0) S |
| Preq: BCH 451, BCH 453/553 |
| Principlies of protein structure and function, protein folding, enzymology, ligand binding, protein transport, and metabolic pathways. |
| Course Offerings: fall sprg | WolfWare Info |
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| BCH (ANS) 571 | Regulation of Metabolism | 3(3-0-0) F,Alt. Yrs.(Odd) |
| Preq: BCH 451, GN 411, a course in physiology, cell biology |
| Study of hormonal, enzymatic and molecular-genetic regulation of carbohydrate and lipid metabolism; emphasis on mammalian species. |
| Course Offerings: fall | WolfWare Info |
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| BCH 590 | Special Topics in Biochemistry | 1-3 F,S,Sum |
| Preq: BCH 451 |
| The study of topics of special interest by small groups of students instructed by members of the faculty. |
| Course Offerings: sum2 sprg | |
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| BCH 601 | Macromolecular Structure | 1(1-0-0) F |
| Preq: BCH 453 or BCH 553; a course in physical chemistry highly recommended |
| Introduction to the current understanding and methods used for the study of structures, thermodynamics and conformational dynamics of proteins, nucleic acids and membranes. |
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| BCH 610 | Special Topics | 1-3 F,S,Sum |
| Preq: BCH 451 |
| The study of topics of special interest by small groups of students instructed by members of the faculty. |
| Course Offerings: fall sprg | |
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| BCH 615 | Special Topics In Biochemistry | 1-3 F,S,Sum |
| Preq: Graduate standing in BCH |
| Critical study of special problems and selected topics of current interest in biochemistry and related fields. |
| Course Offerings: fall sum1 sum2 | |
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| BCH 660 | Free Radicals In Toxicology | 1(1-0-0) |
| Preq: BCH 451 and TOX 710 |
| Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms |
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| BCH 670 | Laboratory Rotations | 1(1-0-0) F,S,Sum |
| Preq: BCH 451 |
| Performance of highly directed research by biochemistry students in one or more laboratories of student's choice prior to beginning thesis research. Each laboratory experience lasts 5 weeks and given 1 hr. of credit. No more than 4 credits earned inBCH 692. |
| Course Offerings: fall sprg | |
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| BCH 685 | Master's Supervised Teaching | 1-3 F,S,Sum |
| Preq: Master's student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sprg | |
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| BCH 688 | Non-Thesis Masters Continuous Registration - Half Time Registration | 1(1-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc. |
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| BCH 689 | Non-Thesis Master Continuous Registration - Full Time Registration | 3(3-0-0) F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester. |
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| BCH 690 | Master's Examination | 1-3 F,S,Sum |
| Preq: Master's student |
| For students in non-thesis master's programs who have completed all other requirement of the degree except preparing for and taking the final master's exam. |
| Course Offerings: sprg | |
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| BCH 693 | Master's Supervised Research | 1-9 F,S,Sum |
| Preq: Master's student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 695 | Master's Thesis Research | 1-9 F,S,Sum |
| Preq: Master's student |
| Thesis research |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 696 | Summer Thesis Research | 1(1-0-0) Sum |
| Preq: Master's student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 | |
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| BCH 699 | Master's Thesis Preparation | 1-3 F,S,Sum |
| Preq: Master's student |
| For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 701 | Macromolecular Structure | 3(3-0-0) F |
| Preq: BCH 453 or BCH 553; a course in physical chemistry highly recommended |
| Introduction to the current understanding and methods used for the study of structures, thermodynamics and conformational dynamics of proteins, nucleic acids and membranes. |
| Course Offerings: fall | |
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| BCH 703 | Macromolecular Synthesis and Regulation | 3(3-0-0) F |
| Preq: BCH 453 or BCH 553 |
| Biochemistry of DNA replication, transcription, RNA processing and translation. Development of key concepts, techniques and applications relating to mechanisms and regulation of these processes by analysis of primary literature. |
| Course Offerings: fall | |
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| BCH 705 | Molecular Biology Of the Cell | 3(3-0-0) S |
| Preq: BCH 701 or BCH 703 |
| Regulation of cellular processes, membrane structure and function, signal transduction, protein trafficking/sorting, secretion, photosynthesis and nitrogen fixation. |
| Course Offerings: sprg | WolfWare Info |
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| BCH 751 | Biophysical Chemistry | 3(3-0-0) F,Alt. Yrs. |
| Preq: BCH 451; one sem. of physical chemistry |
| Fundamental and practical aspects of biological macromolecular structure, thermodynamics, hydrodynamics, kinetics and spectroscopy with emphasis on mechanisms in functionally important structural transformations. |
| Course Offerings: fall sprg | WolfWare Info |
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| BCH (GN) 761 | Advanced Molecular Biology Of the Cell | 3(3-0-0) S,Alt. Yrs. |
| Preq: BCH 703 and 705 |
| An advanced treatment involving integrated approaches to biological problems at the molecular level, encompassing biochemistry, cell biology and molecular genetics. Broad, multidisciplinary approaches to solving research problems in biology and thecritical study of primary scientific literature, the development of a research proposal, oral presentations and class discussions. |
| Course Offerings: sprg | |
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| BCH 763 | Biochemistry Of Hormone Action | 3(3-0-0) S,Alt. Yrs |
| Preq: BCH 705 or GN 757 |
| Study of well-defined models of steroid and protein hormone action via lectures, assigned readings and discussions. Students add breadth to the course and depth to their own understanding by searching the literature and writing or lecturing about a particular hormone of their own choosing. |
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| BCH (GN) 768 | Nucleic Acids: Structure and Function | 3(3-0-0) S. Alt.Yrs |
| Preq: BCH 701 and 703 |
| Study of well-defined models of steroid and protein hormone action via lectures, assigned readings and discussions. Students add breadth to the course and depth to their own understanding by searching the literature and writing or lecturing about a particular hormone of their own choosing. |
| Course Offerings: sprg | |
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| BCH 801 | Seminar In Biochemistry | 1(1-0-0) F,S |
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| Course Offerings: fall sprg | |
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| BCH 810 | Special Topics | 1-3 F,S,Sum |
| Preq: BCH 451 |
| The study of topics of special interest by small groups of students instructed by members of the faculty. |
| Course Offerings: fall sprg | |
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| BCH 815 | Advanced Special Topics | 1-3 F,S,Sum |
| Preq: Graduate standing in BCH |
| Critical study of special problems and selected topics of current interest in biochemistry and related fields. |
| Course Offerings: sprg | |
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| BCH 860 | Free Radicals in Toxicology | 1(1-0-0) |
| Preq: BCH 451 and TOX 710 |
| Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms. |
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| BCH 870 | Laboratory Rotations | 1(1-0-0) F,S,Sum |
| Preq: BCH 451; Consent of Instructor |
| Performance of highly directed research by biochemistry students in one or more laboratories of student's choice prior to beginning thesis research. Each laboratory experience lasts 5 weeks and given 1 hr. of credit. No more than 4 credits earned inBCH 692. |
| Course Offerings: fall sprg | |
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| BCH 885 | Doctoral Supervised Teaching | 1-3 F,S,Sum |
| Preq: Doctoral student |
| Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. |
| Course Offerings: fall sprg | |
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| BCH 890 | Doctoral Preliminary Examination | 1-9 F,S,Sum |
| Preq: Doctoral student |
| For students who are preparing for and taking written and/or oral preliminary exams. |
| Course Offerings: fall sprg | |
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| BCH 893 | Doctoral Supervised Research | 1-9 F,S,Sum |
| Preq: Doctoral student |
| Instruction in research and research under the mentorship of a member of the Graduate Faculty. |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 895 | Doctoral Dissertation Research | 1-9 F,S,Sum |
| Preq: Doctoral student |
| Dissertation research |
| Course Offerings: fall sum1 sum2 sprg | |
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| BCH 896 | Summer Dissertation Research | 1(1-0-0) Sum |
| Preq: Doctoral student |
| For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. |
| Course Offerings: sum1 sum2 | |
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| BCH 899 | Doctoral Dissertation Preparation | 1-3 F,S,Sum |
| Preq: Doctoral student |
| For students who have completed all credit hours, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations. |
| Course Offerings: fall sum1 sum2 sprg | |